Endocrine Abstracts

Neuroendocrine tumor (ENET) is a distinct term and includes specific selected tumors of the foregut, midgut and hindgut. The term separates other neurocrest-derived tumors likewise pheochromocytomas, paragangliomas as well as medullary thyroid carcinoma and parathyroid adenoma. There are sporadic and hereditary ENETs. The prominent hereditary group of ENETs forms the syndrome of multiple endocrine neoplasia type 1 (MEN1). Other ENETS are regarded as sporadic.<p class="abst...

Objective: To document influences of sampling of blood under supine fasting versus seated non-fasting conditions on diagnosis of pheochromocytoma using plasma concentrations of normetanephrine, metanephrine and methoxytyramine (P-NMN/MN/MTY).Design and methods: P-NMN/MN/MTY were measured by liquid chromatography with tandem mass spectrometry in 695 patients at five centers, two of which complied with requirements for supine sampling after an overnight fa...